Square Feet
Available Square Feet
SF Floor Plate
Slab to Slab
LEED Rating

Features + Amenities

  • Cambridge Innovation Center – Coworking spaces available on 2nd floor
  • Havana room conference center / kitchen
  • Venture Café – every Thursday from 3 pm. to 8 p.m on 2nd floor
  • Cortex Commons – adjacent to lobby for outdoor events and programming
  • Park Avenue Coffee – coffee, full service lunch
  • Aloft Hotel – across the street
  • Washington University Technology Transfer office on 1st floor
  • MetroLink station – just a few steps from the lobby


Cortex Commons
View Property
Cortex Commons
Cortex 1
View Property
Cortex 1
4220 Duncan
View Property
4220 Duncan
4240 Duncan
View Property
4240 Duncan

Tenants at 4240 Duncan

Knowledge Community

Cortex Innovation Community

A vibrant business, innovation, and technology district in St. Louis.

Explore Contact our St. Louis team

Healthy Buildings Platform

@4240 features enhanced cleaning and disinfecting of all common areas and stairwells; entry and exit door designation; increased outside air circulation; self cleaning surfaces in common areas; and additional hand sanitizers located through the building.

Learn More


Ready to Lease or Want Additional Information?

"*" indicates required fields

This field is for validation purposes and should be left unchanged.

Explore More Wexford Properties

St. Louis, MO
Cortex 1
St. Louis, MO
4220 Duncan
St. Louis, MO
Phoenix, AZ
850 PBC
Pittsburgh, PA
The Assembly
Philadelphia, PA
3675 Market
Winston-Salem, NC
Bailey Power Plant
Miami, FL
Converge Miami